TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks Molecular biology; Neurodegenerative diseases; TDP2 ; CRISPR-Cas9 ; R-loops; Topoisomerase I; DNA double-strand breaks; SCAN1 ; Transcription. DNA...
Focus research 2022 SIGNATHER team
Focus research 2022 SIGNATHER team Development of a technique to identify RHO GTPase inhibitors The SIGNATHER team has developed a new technique based on the coupling of phage display and green fluorescent protein fractionation (split-GPF) to identify intracellular...
The level of von Willebrand factor is a pronostic marker in patients with metastatic melanoma treated by immune checkpoint inhibitors
The level of von Willebrand factor is a pronostic marker in patients with metastatic melanoma treated by immune checkpoint inhibitors Immunotherapy; Melanoma; Translational Medical Research; Tumor Microenvironment. Laura Keller- Team SIGNATHER : Cell Signalling,...
Fighting bronchial cancers
Fighting bronchial cancers As part of the “No Smoking Month 2022”, the Toulouse Cancer Health Foundation presents the project led by Olivier Calvayrac, CNRS research fellow and Pr Julien Mazières, Head of the Pneumology Department at the Toulouse...