LABEX TOUCAN
Toulouse Cancer Laboratory of Excellence

The Toulouse Cancer Laboratory of Excellence is a project that aims to understand the mechanisms of resistance and relapse in blood cancers and by extension in certain solid cancers.

A word from the director:

“We believe that these integrative approaches on massive data will provide an inexhaustible source of information on resistance phenomena in oncology that can potentially be exploited (biomarkers and therapeutic targets) while providing original training for our thesis students via an ambitious international doctoral programme.”

Prof. Pierre Brousset
Scientific Director of Labex Toucan

teams and platforms

Team

S. PYRONNET
AND F. MEGGETTO

R’n Blood :

RNA Biology In Hematologic Tumors

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Team

C. LAURENT

NoLymIT :

New Immunotherapies Against Lymphoma

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TEAM

H. AVET-loiseau
et l. martinet

GENIM :

Genomic And Immunology Of Myeloma

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team

J.E. SARRY

METAML :

Metabolism And Therapeutic Resistance In Acute Myeloid Leukemia

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Team

S. VALITUTTI

DynAct :

Molecular Dynamics Of Lymphocyte Interactions

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TEAM

J.P. GIRARD

Vascular biology

Endothelial cells in Immunity, Inflammation and Cancer

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PLATFORM

IMAG’IN

Labelled Ibisa

Imag’IN is a technological platform offering its expertise for the study, implementation and analysis of projects involving histopathology, functional anatomy and biological imaging techniques.
In particular, we have recognised expertise in virtual microscopy and image analysis.

Team

BIOINFORMATICs IUCT

Bioinformatics Unit
IUCT – CRCT

The bioinformatics platform of the Toulouse University Cancer Institute (IUCT) and the Toulouse Cancer Research Centre (CRCT) is made up of 12 bioinformaticians, statisticians and computer engineers with multidisciplinary expertise to handle the data generated by the various sequencing, cellular and tissue imaging platforms for research units (CRCT) and the hospital (IUCT) in routine practice. This work is based on a very high-speed computing cluster, GPUs and the development of innovative computing solutions.

THE LABEX

 

 

 

 

 

To find biomarkers of resistance in haematopoietic cancers and potential therapeutic targets to circumvent this resistance.

 

 

 

 

 

 

CHALLENGE

RESEARCH

AXIS

 

 

 

 

Deciphering drug resistance in anaplastic large cell lymphomas expressing the oncogenic tyrosine kinase ALK.

Mapping γδT cells and vasculature in lymphoma: a single-cell study for the localization and functional characterization of cytolytic T cells infiltrating human lymphomas.

Immunometabolic landscape of myeloma associated with the efficacy of anti-CD38 mAbs.

 

 

 

 

 

 

Mitochondrial metabolism supports inhibitor resistance of IDH mutants in acute myeloid leukemia.

ALK-transformed mature T cells restore the characteristics of early thymus progenitors.

FAK activity in cancer-associated fibroblasts is a prognostic marker and a key metastatic drug player in pancreatic cancer

 

 

 

 

results

THE LABEX IN FIGURES

ENGINEERS & TECHNICIANS

DOCTORAL STUDENTS

RESEARCHERS & PERMANENT RESEARCH TEACHERS

HOSPITAL PRACTITIONERS

LABEX & TRAINING

 

CARe Graduate School aims to train master and doctoral students in the field of cancer, ageing and rejuvenation.

The Phd Program within the CRCT complements this teaching by inviting students to participate in scientific animation.

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PARTNERSHIPS & FUNDING


ACADEMIC AND HOSPITAL PARTNERS

         

 

FINANCIAL SUPPORT FOR THE TOUCAN LABEX PROGRAM

      

Centre de Recherches en Cancérologie de Toulouse

Centre de Recherches en Cancérologie de Toulouse (Oncopole)

Toulouse – FR

Nous contacter

05 82 74 15 75

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