Morphometric analysis of neoplastic cell clusters in high-grade serous ovarian cancer ascites identifies a promising prognostic factor: a retrospective study

29 Apr 2025 | Discover home page, Discover SigDyn

Morphometric analysis of neoplastic cell clusters in high-grade serous ovarian cancer ascites identifies a promising prognostic factor: a retrospective study. Ovarian cancer, Ascites, Cell clustering, Peritoneal disease, Prognostic factor, Cytomorphology,...

Mechanical stress on solid cancer development

15 Apr 2025 | Discover home page, Discover SigDyn

Mechanical stress on solid cancer development Mechanobiology, compression, PancreaticCancer, breastcancer, PI3K, autophagy. DI-LUOFFO Mickael – SigDyn – : Integrated cellular signalling and PI3K isoforms This study provides direct evidence for the role of...

Identification of cancer-associated fibroblasts with an anti-tumoral activity in pancreatic cancer

15 Apr 2025 | Discover home page, Discover Micropanc

Identification of cancer-associated fibroblasts with an anti-tumoral activity in pancreatic cancer Pancreatic cancer, Pancreatic stellate cells, Cancer-associated fibroblasts, Endoplasmic reticulum, Collagen, Extracellular matrix, BiP. Corinne Bousquet –...

A strong internal promoter drives massive expression of YEATS-domain devoid MLLT3 transcripts in HSC and most lethal AML.

15 Apr 2025 | Dicover R'nBlood, Discover home page

A strong internal promoter drives massive expression of YEATS-domain devoid MLLT3 transcripts in HSC and most lethal AML. Hematopoiesis, Acute myeloid leukemia, genetic alteration, alternative transcription, MLLT3. Stéphane Pyronnet – R’n Blood : RNA Biology in...

The PI3K alpha inhibition sensitizes ovarian cancer with PIK3CA mutation to conventional chemotherapy

13 Mar 2025 | Discover home page, Discover SigDyn

The PI3K alpha inhibition sensitizes ovarian cancer with PIK3CA mutation to conventional chemotherapy PI3K signalling, Tumour cell aggregates, Resistance to treatment, Signal-targeted therapies, BYL-719/Alpelisib, Cisplatin, Combination therapy, Mesenchymal stem...

Role of Vps34, presentation at the 2nd Young Scientist Cancer Congress

23 Jan 2025 | Discover home page, Discover SigDyn

Role of Vps34, presentation at the 2nd Young Scientist Cancer Congress  The 2nd Young Scientist Cancer Congress took place on 10-11th October in Montpellier, as an initiative to promote the careers of young scientists and clinicians. Hala Shalhoub, post-doc in the...