Exploring the role of PAX5P80R mutation in B-cell leukemia.

28 May 2025 | Discover home page, Discover IGAALD

Exploring the role of PAX5P80R mutation in B-cell leukemia. B-cell acute lymphoblastic leukemia; PAX5 alterations; primary oncogenic event; PAX5P80R mutation; leukemia initiation; oncogenic transformation; Hif2alpha; Acriflavine. Bastien Gerby – IGAALD  – ...

Identification and characterisation of the cells responsible for the initiation of B-lineage leukaemias

24 Nov 2023 | Discover home page, Discover IGAALD

Identification and characterisation of the cells responsible for the initiation of B-lineage leukaemias B-lineage leukaemias, Oncogenes, Leukaemic stem cells, Leukaemic initiation and transformation. Bastien Gerby  IGAALD team’s Impact of genetic alterations on...

Focus research 2022 IGAALD team

30 Sep 2023 | Discover IGAALD

Focus research 2022 IGAALD team Germline alterations of transcription factors in acute leukemia In collaboration with the University Hospital of Lille, the team coordinated by Cyril Broccardo, identified the PAX5R38H mutation in a family in which all three children...

Acquired genetic abnormalities predict outcome in patients with GATA2 deficiency

15 Mar 2023 | Discover home page, Discover IGAALD

Acquired genetic abnormalities predict outcome in patients with GATA2 deficiency GATA2, leukemic transformation, clonal hematopoiesis, STAG2, genotype-phenotype correlation, Laétitia Largeaud team IGGALD- Impact of genetic alterations on acute leukemia development...

The Roland Garigou Foundation for Culture & Health awards several prizes and grants to the CRCT in 2022

15 Nov 2022 | Dicover R'nBlood, Discover home page, Discover IGAALD, Discover ImPact, Discover Micropanc, Discover RADOPT, Discover Signather

The Roland Garigou Foundation for Culture & Health awards several prizes and grants to the CRCT in 2022 The Fonroga Foundation supports initiatives and achievements in the fields of culture and health in the Toulouse region. On 15 November 2022 it awarded several...

In search of the cells that cause pediatric leukemia.

17 Dec 2021 | Discover home page, Discover IGAALD

In search of the cells that cause pediatric leukemia. Acute lymphoblastic leukemia Oncogenic transcription factor (Pre-)leukemic stem cells Oncogenic reprogramming Cellular plasticity Self-renewal Initiation and leukemic transformation. Bastien Gerby, team IGAALD :...