The regulation of mRNA translation by RNA G-quadruplex structures contributes to cancer progression and resistance to treatment
The regulation of mRNA translation by RNA G-quadruplex structures contributes to cancer progression and resistance to treatment Cancer, translation, traduction d’ARNm, RNA G-Quadruplex, RNA-binding proteinsG-quadruplexe ARN. Anne Cammas – RNAreg Team’s...
New publication on Autophagy
New publication on Autophagy Liver cancer chloroquine cholangio carcinoma therapy microbial metabolite cell death butyrate, oxidative stress Hala Shalhoub – Equipe SigDyn – Integrated cellular signalling and PI3K isoforms Our cells can eat itself through a...
TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks Molecular biology; Neurodegenerative diseases; TDP2 ; CRISPR-Cas9 ; R-loops; Topoisomerase I; DNA double-strand breaks; SCAN1 ; Transcription. DNA...
Human genetic defects of sphingolipid synthesis
Human genetic defects of sphingolipid synthesis Ceramide ; peripheral neuropathy Glycosphingolipid ; peripheral neuropathy; Ichthyosis ; neurodevelopment; Thierry Levade – Team Melasphinx – Ceramide metabolism in melanoma: from basic mechanisms to...