Focus research 2022 MICROPANC team

Research coordinated by Dr Corinne Bousquet and Prof Cindy Neuzillet (Institut Curie – Saint Cloud) based on bioinformatics and immunohistochemical analyses on a large number of patients with pancreatic adenocarcinoma has identified molecular signatures associated with different original subpopulations of cancer-associated fibroblasts, two of which are prognostic and help in defining specific subtypes of immune, anti-tumor or immuno-suppressive stroma. Identifying these stromal signatures could enable better molecular stratification of tumors and hasten personalized medicine in this cancer, which remains a therapeutic failure. Read the article

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