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Abstract : Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and lethal cancer with worryingly increasing incidence in developed countries. Key aspects that underline PDAC aggressiveness are the pronounced desmoplasia and the metabolic adaptability, features that are commonly found in the primary and the metastatic site. Desmoplasia refers to the enhanced production and deposition of […]

Biosketch: Jonas Teuwen is the Group Leader of the AI for Oncology Lab at the Netherlands Cancer Institute. He was previously a tenure-track assistant professor at the Radboud University Medical Center. Previous he was a postdoc in medical image analysis at the same institute. He obtained his PhD in 2016 in Mathematics and Physics from […]

Crosstalks between Death Receptor signalling and the endoplasmic reticulum stress response in cancer Interactions entre la signalisation des récepteurs de mort et la réponse au stress du réticulum endoplasmique dans le cancer. Elodie Lafont Throughout tumour development, cancer cells are subjected to both intrinsic and extrinsic stresses with which they must cope to survive and […]

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Multiscale Modeling of Biological Systems: Integrating Metabolism, ECM Dynamics, and AI-Driven Workflows within the PhysiCell Framework Multiscale models provide a powerful means of studying complex biological processes across multiple spatial and temporal scales. They capture both intracellular events, such as signaling and metabolism, and extracellular interactions where cells communicate and coordinate. By revealing how genetic […]

Conférence | From the clinic to the bench, and back to the clinic: applications of clinical pharmacogenetics in breast cancer, Maud Maillard - équipe DIAD

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