Kremen1 induces SEC24C/ATG9A-dependent cell death in cancer cells. Kremen1 is a receptor for Dickkopf (DKK) ligands which are WNT inhibitors. It has also been reported to induce cancer cell death in the absence of its ligand, DKK1; however, the precise mechanism underlying Kremen1-mediated cell death remains unclear. Our observations indicate that Kremen1 induces a form […]
Soutenance de thèse de Camille Guyon, équipe SigDyn Plasticité du pancréas exocrine, cancérogenèse et implication de la PI3Kinase VPS34
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Soutenance de thèse de Célia Ramade, équipe T2i
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Identifying the Epigenetic Players Involved in Melanoma Resistance to Targeted Therapies and to the Immune System. Since 2011-2012 and the use of targeted therapies and immunotherapies in the treatment of metastatic melanoma, progress in terms of patient survival is evident, with an increase in median survival from less than a year to over 5 years […]
