{"id":51573,"date":"2022-10-10T15:39:56","date_gmt":"2022-10-10T13:39:56","guid":{"rendered":"https:\/\/www.crct-inserm.fr\/?page_id=51573"},"modified":"2022-10-25T11:53:12","modified_gmt":"2022-10-25T09:53:12","slug":"neovirtech","status":"publish","type":"page","link":"https:\/\/www.crct-inserm.fr\/neovirtech\/","title":{"rendered":"NeoVirTech"},"content":{"rendered":"

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NeoVirTech<\/h1>\n

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NeoVirTech<\/strong>
<\/strong><\/h2>\n

[\/et_pb_text][et_pb_divider _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.crct-inserm.fr\/wp-content\/uploads\/2022\/10\/IMG_6596-scaled.jpg” title_text=”IMG_6596″ _builder_version=”4.17.3″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ disabled_on=”on|on|on” _builder_version=”4.16″ _module_preset=”default” width=”50%” disabled=”on” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.crct-inserm.fr\/wp-content\/uploads\/2021\/03\/LOGO-TOUCAN-Horizontal.png” title_text=”LOGO-TOUCAN-Horizontal” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”22px” global_colors_info=”{}”]<\/p>\n

Le laboratoire d\u2019Excellence Toulouse Cancer est un projet qui vise \u00e0 comprendre les m\u00e9canismes de r\u00e9sistance et de rechute dans les cancers.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” use_background_color_gradient=”on” background_color_gradient_stops=”rgba(43,135,218,0) 50%|#f2efef 50%” background_color_gradient_start=”rgba(43,135,218,0)” background_color_gradient_start_position=”50%” background_color_gradient_end=”#f2efef” background_color_gradient_end_position=”0%” custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_row disabled_on=”on|on|on” _builder_version=”4.16″ _module_preset=”default” custom_padding=”0px||0px|||” disabled=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=FkQuawiGWUw” image_src=”https:\/\/www.crct-inserm.fr\/wp-content\/uploads\/2021\/03\/video.jpg” _builder_version=”4.16″ _module_preset=”default” width=”80%” module_alignment=”center” global_colors_info=”{}”][\/et_pb_video][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” background_color=”#f2efef” custom_padding=”0px||0px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.17.3″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

NeoVirTech SAS d\u00e9veloppe des virus et des vecteurs viraux autofluorescents pour l’imagerie et la d\u00e9couverte de nouveaux candidats m\u00e9dicaments antiviraux dans les domaines de la sant\u00e9 humaine, de la sant\u00e9 animale et de la biod\u00e9fense. La soci\u00e9t\u00e9 dispose d’un catalogue de virus et de vecteurs fluorescents en constante extension et s’appuie sur sa technologie propri\u00e9taire ANCHOR\u2122, la seule technique non invasive permettant la d\u00e9tection de l’ADN \u00e0 l’int\u00e9rieur des cellules vivantes. Depuis la pand\u00e9mie de Covid19, la soci\u00e9t\u00e9 participe activement \u00e0 la validation d\u2019antiviraux dirig\u00e9s contre le SARS-CoV-2 et \u00e0 la validation des proc\u00e9dures de d\u00e9sinfection.<\/p>\n

NeoVirTech a r\u00e9cemment rejoint le CRCT pour d\u00e9velopper ses activit\u00e9s en oncologie en \u00e9troite collaboration avec les chercheurs du CRCT et les cliniciens de l’Institut Universitaire du Cancer de Toulouse Oncopole. Au sein du CRCT, NeoVirTech partage sa technologie propri\u00e9taire ANCHORTM<\/sup> pour \u00e9tudier la dynamique de la r\u00e9gulation de l\u2019expression g\u00e9nique dans les cellules vivantes, et met aussi \u00e0 disposition son expertise dans la conduite de campagnes de criblage \u00e0 haut contenu utilisant des chimioth\u00e8ques. Le programme phare du CRCT et de NeoVirTech consiste au d\u00e9veloppement de nouveaux virus oncolytiques pour la th\u00e9rapie du cancer, en \u00e9troite collaboration avec l’\u00e9quipe ImPACT du CRCT. En bref, les partenaires ont pour ambition de mettre en place une plateforme th\u00e9ranostique pour \u00e9tudier l’efficacit\u00e9 antitumorale des virus oncolytiques dans des mod\u00e8les pr\u00e9cliniques, afin de s\u00e9lectionner au mieux les patients pouvant b\u00e9n\u00e9ficier de cette th\u00e9rapie innovante et pour identifier des combinaisons pour augmenter l’efficacit\u00e9 de la viroth\u00e9rapie.<\/p>\n

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Signalisation oncog\u00e9nique<\/p>\n

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RTK\/RAS\/MAPK<\/p>\n

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RHOGTPases<\/p>\n

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Cancer du poumon<\/p>\n

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NOS PROJETS<\/strong>
DE RECHERCHE<\/h2>\n

[\/et_pb_text][et_pb_divider _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=”on” gutter_width=”2″ disabled_on=”on|on|on” _builder_version=”4.17.3″ _module_preset=”default” custom_padding=”||0px|||” disabled=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_blog fullwidth=”off” posts_number=”20″ include_categories=”351″ use_manual_excerpt=”off” show_more=”on” show_author=”off” show_date=”off” show_categories=”off” masonry_tile_background_color=”#f2efef” _builder_version=”4.16″ _module_preset=”default” header_level=”h3″ header_font=”|800|||||||” header_font_size=”20px” body_font_size=”20px” read_more_text_color=”#5EC7ED” read_more_font_size=”20px” read_more_line_height=”3em” background_enable_color=”off” border_width_all=”0px” global_colors_info=”{}”][\/et_pb_blog][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” _builder_version=”4.17.3″ _module_preset=”default” custom_padding=”||0px|||” disabled=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”448e09ae-9652-4ead-bc5f-152c7adf1202″ global_colors_info=”{}”]<\/p>\n

LES FOCUS<\/strong>
DE L\u2019\u00c9QUIPE<\/h2>\n

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D\u00e9couvrir<\/h4>\n

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Comprendre<\/h4>\n

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Participer<\/h4>\n

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En live<\/strong><\/h2>\n

[\/et_pb_text][et_pb_divider _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][et_pb_code _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]\n\n

\n\t\n \n
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\n CRCT-Oncopole<\/span>\n <\/span>\n Suivre<\/span>\n \n <\/path><\/svg>1,220<\/span>\n <\/path><\/svg>1,117<\/span>\n <\/span>\n <\/p>\n

\n Compte officiel du Centre de Recherches en Canc\u00e9rologie de Toulouse <\/p>\n <\/div>\n

\n
\n <\/path><\/svg> <\/div>\n \"crctoncopole\"\n <\/div>\n <\/a>\n<\/div>\n\n
\n \n
\n\n \n
\n
\n \n \"crctoncopole;\n <\/a>\n \n CRCT-Oncopole<\/a>\n @crctoncopole<\/a>\n \n \t\t ·<\/span>\n\t
\n 21 Ao\u00fbt 1693609681678217706<\/span><\/a>\n <\/div>\n <\/div>\n
\n <\/path><\/svg> <\/div>\n <\/div>\n\n
\n \t\t\t\t

Castelnau-Montratier c\u00e9l\u00e8bre la lutte contre le cancer. Jeudi 24 ao\u00fbt 2023 conf\u00e9rence avec Fr\u00e9d\u00e9ric Chibon responsable de l'\u00e9quipe @OncoSarc du @crctoncopole accompagn\u00e9 de Gwena\u00ebl Ferron et Martin Gauthier oncologue @IUCTOncopole
\nD\u00e9couvrir l'\u00e9quipe
\n\u27a1\ufe0fhttps:\/\/www.crct-inserm.fr\/oncosarc\/ <\/p>\n\t\t\t\t\t\t\n \n

\n \n \n <\/path><\/svg>
<\/path><\/svg><\/div>\n \n \"Image\n \n Image du flux Twitter.<\/span> <\/a>\n \n <\/div>\n\n\t \n \n <\/div>\n \n\t\n
\n \n <\/path><\/g><\/svg> R\u00e9pondre sur Twitter 1693609681678217706<\/span>\n <\/a>\n\n \n <\/path><\/svg> Retweeter sur Twitter 1693609681678217706<\/span>\n 0<\/span>\n <\/a>\n\n \n <\/path><\/g><\/svg> J\u2019aime sur Twitter 1693609681678217706<\/span>\n 6<\/span>\n <\/a>\n\n \n Twitter<\/span>\n 1693609681678217706<\/span>\n <\/a>\n \n\t<\/div>\n\n\t<\/div>\n\n <\/div>\n\n Voir plus<\/span><\/a>\n\n<\/span>\n<\/div>\n[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” _builder_version=”4.17.3″ _module_preset=”default” background_color=”#f2efef” disabled=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.17.3″ _module_preset=”448e09ae-9652-4ead-bc5f-152c7adf1202″ global_colors_info=”{}”]<\/p>\n

PRODUCTIONS SCIENTIFIQUES<\/strong><\/h2>\n

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Martins, Carla Silva, Cyntia Taveneau, Gerard Castro-Linares, Mikhail Baibakov, Nicolas Buzhinsky, Mar Eroles, Violeta Milanović, et al. “Human Septins in Cells Organize as Octamer-Based Filaments Mediating Actin-Membrane Anchoring.” Preprint. Cell Biology, February 24, 2022. https:\/\/doi.org\/10.1101\/2022.02.23.481653.<\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n\n

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Calvayrac, Olivier, Ada Nowosad, Stéphanie Cabantous, Lin-Po Lin, Sarah Figarol, Pauline Jeannot, Murielle P. Serres, et al. “Cytoplasmic P27Kip1 Promotes Tumorigenesis via Suppression of RhoB Activity.” The Journal of Pathology<\/i> 247, no. 1 (January 2019): 60–71. https:\/\/doi.org\/10.1002\/path.5167<\/a>.<\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n\n

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LES MEMBRES DE L\u2019\u00c9QUIPE<\/strong><\/h2>\n

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Sandrine Kappler-Gratias<\/a><\/div>\n
Chercheur invit\u00e9 \/ visiting researcher<\/div><\/div>\n<\/div><\/div><\/div> <\/div>\n
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Franck Gallardo<\/a><\/div>\n
Chercheur invit\u00e9 \/ visiting researcher<\/div><\/div>\n<\/div><\/div><\/div> <\/div>\n
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Charlotte Quentin-Froignant<\/a><\/div>\n
Chercheur invit\u00e9 \/ visiting researcher<\/div><\/div>\n<\/div><\/div><\/div> <\/div>\n
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Elie Marcheteau<\/a><\/div>\n
Chercheur invit\u00e9 \/ visiting researcher<\/div><\/div>\n<\/div><\/div><\/div> <\/div>\n <\/div>\n<\/div><\/div>\n\n
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