No relevant follicular lymphoma models for in vitro studies have been characterized in depth. Here, we present a robust and reliable 3D cell model characterized by 2D and 3D imaging. This model allows an increased throughput for drug testing and opens new perspectives for preclinical studies. Finally, this study warns the scientific community of possible misinterpretations following 2D imaging and encourage the use of 3D imaging for in depth characterization and drug effect determination.
Virtual EACR Poster session 2021 by Carla Faria PhD inCRCT Team 9.