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Dr. Luca Grumolato: nouveaux modèles de résistance du cancer bronchique à la thérapie ciblée dans un contexte d’hétérogénéité intratumorale

vendredi 16 février 2018 - 11:00 à 13:00

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Nouveaux modèles de résistance du cancer bronchique à la thérapie ciblée dans un contexte d’hétérogénéité intratumorale

Luca Grumolato, PhD

  • M.Sc. in Molecular Biology, University of Torino, Italy
  • Ph.D. in Cell Biology, University of Rouen, France
  • Post-Doctoral Fellow, Department of Oncological Sciences, Mount Sinai School of Medicine, New York, USA (Stuart Aaronson’s lab)
  • Habilitation à diriger des recherche (HDR)

Research areas: cell signaling in cancer, targeted therapy, drug resistance, tumor heterogeneity

Short description of research activities: our group focuses on the molecular mechanisms and the biological implications of signaling pathway activation in cancer. The evolution of multicellular organisms has involved the development of intercellular communication required for processes such as embryonic development, tissue differentiation, and systemic responses to wounds and infections. These complex signaling networks are in large part mediated by growth factors, cytokines and hormones. In normal conditions, such factors can influence cell proliferation in positive or negative ways, as well as induce a series of differentiated responses in appropriate target cells. Aberrant activation of signaling pathways through different mechanisms contributes to the development and progression of most if not all human cancers.

Détails

Date :
vendredi 16 février 2018
Heure :
11:00 à 13:00

Organisateur

Gilles Favre
Téléphone :
+33(0) 5 82 74 15 75
E-mail :
favre.gilles@iuct-oncopole.fr

Lieu

Salle C. Cazaux
2 Avenue Hubert Curien
Toulouse, 31100 France Métropolitaine
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