DR. MARC POIROT
IDENTIFICATION AND CHARACTERIZATION OF
NEW STEROL METABOLITES
The recent identification of the enzyme that produces dendrogenin A, as well as its structural characterization, has led us to postulate the existence of other metabolites produced in the same way. Two new bioactive metabolites, in addition to dendrogenin A and with specific biological properties have already been identified. The other candidates will be chemically synthesized, their biological properties predicted in silico and established in vitro. These new molecules will be investigated as metabolites in biological fluids and extracts.
Our goal is to complete the characterization of this new metabolic branch of cholesterol.