The work presented in this article is based on a clinical observation: 3 children from the same family all suffered from B-acute lymphoblastic leukemia (B-ALL). Knowing that it is a very rare disease, we suspected a genetic predisposition and by reading the genome of...

Radiotherapy is one of the therapeutic weapons with the surgery of local cancer treatment. Radiation therapy involves exposing part of the body to ionizing radiation. The principle of ionizing radiation is to deliver a certain amount of energy, the importance of which...

Coordinated by the European Biomedical Imaging Research Institute (EIBIR, Austria), the H2020 MEDIRAD project (http://www.medirad-project.eu) is based on a consortium of 33 partners representing 14 European countries. This project aims to explore the effects of...

Pancreatic ductal adenocarcinoma (PDAC) is a cancer with a poor prognosis (5-year survival rate of less than 7%). Its stroma, composed mainly of cancer-associated fibroblasts (CAF), contributes to the aggressiveness of this tumour. In this study we identify that the...

While many cellular mechanisms leading to chemotherapy resistance have been identified, there is a growing awareness that mechanical properties of tumours, such as their ability to deform, could contribute to the inefficiency of treatments. Here, when we talk about...