CRCT News
Publication team 2 (J.S. Hoffmann) / ARTEMIS and XPF-ERCC1: 2 nucleases to prevent genetic instability
Bétous, R., Goullet de Rugy, T., Pelegrini, A.L., Queille, S., de Villartay, J.-P., & Hoffmann, J.-S.*, 2018. DNA replication stress triggers Rapid DNA Replication Fork Breakage by Artemis and XPF. PLoS Genet. 14, e1007541. DNA replication stress (DRS) leads to...
Focus: collaboration between Pierre Cordelier’s team & Neovirtech on oncolitic viruses
Discover in this France 3 TV report the collaboration between the CRCT team led by Dr. Pierre Cordelier and the Toulouse start-up Neovirtech: a therapeutic innovation opening up new perspectives in the treatment of cancer. [video width="960" height="540"...
Focus: IMMUSPHINX program – Targeting sphingolipid metabolism to improve the efficacy of immunotherapies in melanoma
Thanks to anticancer immunotherapies targeting immune checkpoints, the proportion of patients with metastatic melanoma (MM) in remission after 5 years has tripled during the last years. However, therapeutic options are sparse for patients who do not respond to...
Open position: post-doctoral fellow (team 13)
Profile We seek a highly motivated scientist that hold a Ph.D in immunology with a strong background in cellular immunology, cell signaling and experience in mouse models. Good track record, communication, technical and organizational skills are expected. Offer The...
New publication in Nature Communications !
Dendrogenin A drives LXR to trigger lethal autophagy in cancers Dendrogenin A, a metabolite of cholesterol, has tumor suppressive properties but the mechanisms of action were until know unknown. In this collaborative work between team 12 of the CRCT (Marc &...
Hervé Avet-Loiseau awarded with FRM Prize Rosen 2017
Pr. Hervé Avet-Loiseau, Director of CRCT's team 13 "Pharmacogenomics of multiple myeloma" and Director of IUCT-O's Unit "Genomics of Myeloma" is laureate of the 2017 Prize Rosen from the Fondation pour la Recherche Médicale (FRM) More information here.