CRCT News
Congratulation to Benoît Thibault, Axis 1 poster prize during the 16th Cancéropôle GSO Days
An unmissable event for researchers and clinicians from the Greater South-West, the Annual Days are a place for exchange, providing an opportunity to take stock of the Cancéropôle's programmes and strategic areas of focus. These meetings encourage closer links between...
New combined therapy to promote self-digestion and death of lymphoma cells expressing the ALK oncogene
The ALK oncogene (Anaplastic Lymphoma Kinase) is a constitutively active tyrosine kinase involved in an increasing number of cancers. Initially identified as being responsible for the majority of pediatric anaplastic large cell lymphomas, its involvement in a wider...
T-lymphocytes transformed in the laboratory help to better understand the origin of a child’s lymphoma.
Anaplastic large cell lymphoma is one of the most common pediatric T-lymphomas. It mainly affects CD4 lymphocytes (major guardian of the immune system) and is associated in more than 80% of cases with the NPM-ALK chromosomal translocation (which is the transfer of...
How much does genetics and other medications impact the effect of tamoxifen treatment in breast cancer ?
Plasma concentrations of endoxifen, the main active metabolite of tamoxifen, show large differences between individuals due to genetic and demographic factors as well as concomitant treatments. This study evaluates the impact of genetic differences and other...
Identification of a new mutation that predisposes to leukemia
The work presented in this article is based on a clinical observation: 3 children from the same family all suffered from B-acute lymphoblastic leukemia (B-ALL). Knowing that it is a very rare disease, we suspected a genetic predisposition and by reading the genome of...
Dosimetric performance of continuous EPID imaging in stereotactic treatment conditions
Radiotherapy is one of the therapeutic weapons with the surgery of local cancer treatment. Radiation therapy involves exposing part of the body to ionizing radiation. The principle of ionizing radiation is to deliver a certain amount of energy, the importance of which...