11 May 2020 | Publications, Research
Cytotoxic T cells (CTL) are essential cellular components in the immune response against viruses and cancer. This is why it is essential to better understand the function of these cells and in particular to better understand how these cells manage to kill their target...
7 Feb 2020 | Publications, Research
Immunotherapy is a treatment that aims to educate our immune system against cancer cells. This treatment resulted in a long-term response in patients with metastatic melanoma (40-60%) with in some cases total tumour regression. The challenge is now that the maximum...
7 Feb 2020 | Publications
Dendrogenin A (DDA) is a tumor suppressor mammalian cholesterol-derived metabolite and a new class of ligand of the Liver X receptor (LXR), which displays tumor cell differentiation. In human and mouse breast adenocarcinoma cells, DDA-induced cell differentiation was...
