by Stephane Cailmail | 31 Jul 2020 | Actualités générales, General news, Publications, Research
For patients with refractory or relapsing testicular cancer after standard chemotherapy, more aggressive chemotherapy with carboplatin and etoposide may be used. After this high-dose chemotherapy, a stem cell transplant is performed to replace those that have been...
by Stephane Cailmail | 27 Jul 2020 | General news, Publications, Research
Metabolic pathways have emerged as cornerstones in carcinogenic deregulation providing new therapeutic strategies for cancer management. This is illustrated by the recent discovery of a cholesterol metabolic branch involving the biochemical transformation of...
by Stephane Cailmail | 10 Jul 2020 | General news, Publications, Research
Pancreatic cancer is a very poor prognosis. It is caused in more than 80% of cases by oncogenic mutations of the protein called Kras. This mutated Kras protein is active by direct interaction of PI3K proteins. Until now, the subtype of Kras mutation was considered...
by Stephane Cailmail | 25 Jun 2020 | Actualités générales, General news, Publications, Research
The fact that many people suffer from more than one disease, known as comorbidity, has become one of the main challenges for the 21st century aging population, as it mainly affects the elderly, decreasing treatment options and patients’ life expectancy while...
by Stephane Cailmail | 2 Jun 2020 | General news, Publications, Research
Some papers including some from our group suggested that the organization of DNA and the genome is like a network. Networks are systems in which many units interact with each other (friends connecting on social media, cities connected by roads, neurons connected in...
by Stephane Cailmail | 7 Feb 2020 | Actualités générales, General news, Publications, Research
Immunotherapy is a treatment that aims to educate our immune system against cancer cells. This treatment resulted in a long-term response in patients with metastatic melanoma (40-60%) with in some cases total tumour regression. The challenge is now that the maximum...
