by Stephane Cailmail | 31 Aug 2021 | General news, Publications, Research
The radiation dose delivered to the patient in radiotherapy is usually calculated using commercial software (“TPS”) which allows a very accurate calculation in the vast majority of clinical cases. However, it is sometimes necessary to have access to a...
by Stephane Cailmail | 16 Jul 2021 | General news, Publications, Research
In this study, we describe the oncogenic role of a novel long noncoding RNA (lncRNA) called LONA (LncRNA Overexpressed in NPM1 mutated Acute myeloid leukemia) overexpressed in patients with acute myeloid leukemia (AML) carrying the mutation of the nucleophosmin NPM1....
by Stephane Cailmail | 18 Jun 2021 | General news, Publications, Research
A tumour cell experiences mechanical forces of compression, traction and shear. These physical forces induce a signal in the cancer cell. The transmission of this signal is very fast and involves deformation of the cell. A huge current research effort is aimed at...
by Stephane Cailmail | 16 Jun 2021 | General news, Publications, Research
Radiation therapy must take into account tumor motion. Indeed, during the treatment the target can move up to several centimeters. This could lead to an under dosage of the target or an over dosage of the Organs at Risk (OARs). For classic treamtment the motion is...
by Stephane Cailmail | 11 Jun 2021 | General news, Publications, Research
Pancreatic cancer is a disease with a poor prognosis that progresses very rapidly after detection to metastatic spread. At detection, the primary tumour may be associated with a so-called micro-metastatic disease which, because it is microscopic, goes unnoticed with...
by Stephane Cailmail | 7 Apr 2021 | General news, Publications, Research
Immunotherapy for advanced melanoma has revolutionized the treatment of this deadly cancer. However, almost half of patients do not respond to this treatment and die within 5 years after starting treatment. Our work shows that melanoma cells exhibit alterations in the...
