BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Centre de Recherches en Cancérologie de Toulouse - ECPv6.15.18//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Centre de Recherches en Cancérologie de Toulouse
X-ORIGINAL-URL:https://www.crct-inserm.fr
X-WR-CALDESC:Évènements pour Centre de Recherches en Cancérologie de Toulouse
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20220327T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20221030T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20230326T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20231029T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20231020T110000
DTEND;TZID=Europe/Paris:20231020T120000
DTSTAMP:20260409T222452
CREATED:20230901T132907Z
LAST-MODIFIED:20231003T125619Z
UID:57200-1697799600-1697803200@www.crct-inserm.fr
SUMMARY:Conférence | Insights into the disruption of gene regulatory programs in cancers | Dr Anthony Mathelier
DESCRIPTION:Pour suivre la conférence à distance\, cliquez ici. \nAbstract: \nMost cancer somatic alterations occur in the noncoding portion of the human genome\, which contains important cis-regulatory regions acting as genetic switches to ensure gene expression occurs at correct times and intensities in correct tissues. However\, the identification of critical noncoding cancer driver events has been mostly limited to a few examples with high recurrence or high functional impact. Transcription factors (TFs) are key proteins binding to cis-regulatory regions at their TF binding sites to modulate the rate of gene transcription. As cancer is a disease of disrupted cellular regulation\, it is critical to analyze these regions to highlight patient somatic mutations and epigenetic modifications altering the gene regulatory program of the cells. In this talk\, I will present our recent works on the interplay between TF binding\, somatic mutations\, and DNA methylation alteration that shifts the gene regulatory program in patients cancer cells.
URL:https://www.crct-inserm.fr/evenement/conference-insights-into-the-disruption-of-gene-regulatory-programs-in-cancers-dr-anthony-mathelier/
LOCATION:Salle Cazaux + Visio Teams
CATEGORIES:Animation scientifique
ATTACH;FMTTYPE=image/png:https://www.crct-inserm.fr/wp-content/uploads/2023/09/Conference-CRCT-Anthony-Mathelier.png
END:VEVENT
END:VCALENDAR